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Description

Description

1-MNA or ‘1-methylnicotinamide’ is a unique supplement that helps block the enzyme NNMT, supporting metabolic, brain, and cellular health by optimizing NAD levels. It is a natural compound produced in the body through the breakdown of niacin, a form of vitamin B3.

1-MNA has been shown to inhibit the enzyme NNMT, which when present in high levels, is associated with various diseases. By inhibiting this enzyme, 1-MNA can contribute to overall cellular health and disease prevention.

Researched extensively for its safety profile, 1-MNA supplementation aims to safely restore NAD levels, optimize cellular redox pathways, and combat age-related diseases comprehensively. As a natural byproduct of vitamin B3, 1-MNA also shows anti-inflammatory effects and supports vascular and cardiovascular health, making it a strong candidate for daily use.

Safely increase NAD levels and block NNMT
Renowned for its anti-inflammatory and anti-thrombotic qualities
Improve cell energy metabolism
Positive effect on Vascular Endothelium
Lowers levels of inflammatory markers

Benefits

Essential for maintaining vascular endothelial function and stimulating synthesis of prostacyclin (PGI2)
Bolsters the secretory function of the vascular endothelium, thereby safeguarding against dysfunction
Minimizes the risk of blood clot formation and inflammation via PGI2 synthesis.
Enhances the stability of sirtuins (Sirt1), which in certain biological models has been associated with extended lifespan
Considered a groundbreaking molecule with potent anti-inflammatory and anti-atherosclerotic effects
Leading research institutions suggest 1-MNA may extend human lifespan
Elevated levels of 1-MNA during exercise and fasting suggest that its consumption, particularly during endurance training, could enhance exercise capacity and improve performance

Ingredients

1-MNA (1-methylnicotinamide chloride) 58mg

Other Ingredients: cellulose, hydroxypropyl methyl cellulose, silicon dioxide.

Each bottle contains 30 capsules 58mg/capsule. Recommended daily dosage is one per day.

Longevity Launch Labs

1-MNA

$69.00

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MSRP = $89.00

For bulk order discounts, please contact sales@medshift.com.

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Endotelio 1-MNA is a unique supplement that helps block the enzyme NNMT, supporting metabolic, brain, and cellular health by optimizing NAD levels. As a natural byproduct of vitamin B3, 1-MNA also shows anti-inflammatory effects and supports vascular and cardiovascular health.

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Description

1-MNA or ‘1-methylnicotinamide’ is a unique supplement that helps block the enzyme NNMT, supporting metabolic, brain, and cellular health by optimizing NAD levels. It is a natural compound produced in the body through the breakdown of niacin, a form of vitamin B3.

1-MNA has been shown to inhibit the enzyme NNMT, which when present in high levels, is associated with various diseases. By inhibiting this enzyme, 1-MNA can contribute to overall cellular health and disease prevention.

Researched extensively for its safety profile, 1-MNA supplementation aims to safely restore NAD levels, optimize cellular redox pathways, and combat age-related diseases comprehensively. As a natural byproduct of vitamin B3, 1-MNA also shows anti-inflammatory effects and supports vascular and cardiovascular health, making it a strong candidate for daily use.

Safely increase NAD levels and block NNMT
Renowned for its anti-inflammatory and anti-thrombotic qualities
Improve cell energy metabolism
Positive effect on Vascular Endothelium
Lowers levels of inflammatory markers

Benefits

Essential for maintaining vascular endothelial function and stimulating synthesis of prostacyclin (PGI2)
Bolsters the secretory function of the vascular endothelium, thereby safeguarding against dysfunction
Minimizes the risk of blood clot formation and inflammation via PGI2 synthesis.
Enhances the stability of sirtuins (Sirt1), which in certain biological models has been associated with extended lifespan
Considered a groundbreaking molecule with potent anti-inflammatory and anti-atherosclerotic effects
Leading research institutions suggest 1-MNA may extend human lifespan
Elevated levels of 1-MNA during exercise and fasting suggest that its consumption, particularly during endurance training, could enhance exercise capacity and improve performance

Ingredients

1-MNA (1-methylnicotinamide chloride) 58mg

Other Ingredients: cellulose, hydroxypropyl methyl cellulose, silicon dioxide.

Each bottle contains 30 capsules 58mg/capsule. Recommended daily dosage is one per day.

Recommended by 250+ US Clinicians

30+ Academic Led Scientific Studies

20+ Years of Research & Innovation

Internationally Recognized Patents

Why Patients Love 1-MNA (and Why It's Essential for NAD+ Protection)

1-MNA acts as a cellular guardian that protects and preserves your NAD+ investment. By blocking the NNMT enzyme that breaks down NAD+, 1-MNA ensures your body keeps more of the NAD+ it needs for optimal cellular function - giving you maximum return on every dose.

What patients experience with this protective partnership:
✅ More energy and better endurance
✅ Reduced inflammation and improved circulation
✅ Faster recovery and stronger performance
✅ Support for healthy aging and longevity

Think of 1-MNA as the shield that ensures NAD+ is working healthily in your system. While NAD+ powers your cellular engines, 1-MNA prevents that power from being wasted - creating a synergistic duo that maximizes your body's natural energy, repair, and longevity processes - making them the ultimate cellular duo.

Suggested Dosing Protocol

Increase NAD, the Safe Way.

1-MNA, short for 1-methylnicotinamide, is a natural compound produced in the body through the breakdown of niacin, a form of vitamin B3.

The molecule works at the cellular level to help balance key molecular pathways involved in NAD regulation and energy, endothelial function, oxidative stress, and longevity.

With multiple patents supporting the novel application of this molecule in supporting a healthy lifestyle, 1-MNA offers an opportunity to address cell health at the deepest level.

Suggested Dosing Protocol

The Only 1-MNA Product on the Market

1-MNA plays a crucial role in regulating NAD metabolism in the body, blocking the enzyme Nicotinamide N-methyltransferase (NNMT), which is a key regulator of the delicate redox balance, thereby restoring cellular health and optimizing NAD levels.

Endotelio's 1-MNA is a high-quality dietary supplement, synthesized through a unique technology developed in collaboration with European universities, manufactured in a GMP-certified facility in Eastern Europe, and has been recognized with awards for its groundbreaking contribution to cellular health.

1-MNA has been recognized for its anti-inflammatory and anti-thrombotic properties, along with its unique ability to improve cell energy metabolism.